Tag Archives: pde5 inhibitor

Avanafil Approval for ED Treatment Sets Men Into Frenzy

After the avanafil approval in the market, a lot of men have started to switch from their old ED pills to avanafil because of the promising benefits of the drug. For your information, avanafil approval has been so recent that it has not yet completely established its own name like Viagra. However, with its advantages that cannot be found with other drugs it is starting to become popular for a lot of men having troubles in their sexual life. Avanafil is the latest ED pill approved with lesser side effects and better results than any of its rival drugs. Continue reading

Solving Erectile Dysfunction with Tadalafil 20 mg

If you believe you may have been suffering from the effects of erectile dysfunction, it is best that you consult with your doctor.  This particular problem cannot be solved in its entirety without proper diagnosis and treatment.  Below are some things you may encounter when trying to find out what are the ideal steps in treating your erectile dysfunction problems.

Treatment of Erectile Dysfunction

Erectile dysfunction is basically treated by means of solving the underlying physical and/or psychological factors that are causing it to occur.  The most common physical factor that causes ED is atherosclerosis, or the narrowing of the arteries.  Such existence of risk issues dictates that one has to make some alterations in lifestyle plus following certain measures in order to maintain blood pressure, blood sugar, as well as cholesterol under control.  Doing regular exercise, cessation of smoking, maintaining a healthy and fit body weight, following a healthy diet regimen, de-stressing, and getting enough sleep each night are some simple but effective measures to keep oneself healthy and therefore avoid suffering from the detrimental effects of erectile dysfunction.

There are actually many kinds of treatment options that have proved themselves very effective for solving erectile dysfunction issues.  A very easy way to solve this dilemma is through the use of medications such as tadalafil 20 mg (brand name Cialis).  Tadalafil 20 mg is an oral medication that is intended for the treatment of impotence/erectile dysfunction as well as benign prostatic hypertrophy.  It belongs to a class of drugs identified as phosphodiesterase type 5 inhibitors, and its brothers are called sildenafil (Viagra) and vardenafil (Levitra).

Penile erection occurs via the filling of blood in the penis.  The blood vessels that carry blood to the penis will grow in size and thus carry more blood to the penis, and, simultaneously, the blood vessels that carry blood away from the penis will become smaller in size and thus remove less blood from the penis.  Erection occurs via sexual stimulation, and this causes the production and discharge of nitric oxide to the penis.  The nitric oxide will then trigger an enzyme called guanylate cyclase and create cyclic guanosine monophosphate (cGMP).  It’s actually the cGMP that’s mainly liable in increasing as well as decreasing blood vessel size that carry blood towards and fro the penile shaft, which causes the erection.  When a specific enzyme called phosphodiesterase type 5 destroys the cGMP, which results to the blood vessels returning back to their normal size, the blood leaves the penile shaft, thus ending the erection.  The action of tadalafil 20 mg is to prevent or inhibit phosphodiesterase type 5 from destroying cGMP, so that the cGMP can stay around and promote erection.  The presence of cGMP for a longer period of time will lead to a more prolonged engorgement of the penis with blood, thus enabling a man to undergo and successfully complete sexual intercourse. Continue reading